The role of non-acid reflux in gastro-oesophageal reflux disease

被引:28
作者
Katz, PO [1 ]
机构
[1] Grad Hosp Philadelphia, Dept Med, Philadelphia, PA 19146 USA
关键词
D O I
10.1046/j.1365-2036.2000.00875.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The role of acid in the pathogenesis of gastro-oesophageal reflux disease (GERD) has been extensively studied and is well accepted. The role, if any, of non-acid reflux, in particular duodenogastro-oesophageal reflux, is much debated. The availability of new technology to detect non-acid reflux has heightened interest in this question. This article reviews the following: How do we define non-acid reflux? Does duodenogastro-oesophageal reflux (alone or in combination) cause oesophageal injury, symptoms or both? What is its role in complicated GERD? What methods are available to assess non-acid reflux? Does non-acid reflux need treatment and if so what modalities are available?
引用
收藏
页码:1539 / 1551
页数:13
相关论文
共 94 条
[1]  
[Anonymous], 1991, J GASTROINTEST MOTIL, V3, P151, DOI DOI 10.1111/J.1365-2982.1991.TB00061.X
[2]  
Attwood S E, 1993, Surg Annu, V25 Pt 2, P151
[3]   BARRETT-ESOPHAGUS - EFFECT OF ANTIREFLUX SURGERY ON SYMPTOM CONTROL AND DEVELOPMENT OF COMPLICATIONS [J].
ATTWOOD, SEA ;
BARLOW, AP ;
NORRIS, TL ;
WATSON, A .
BRITISH JOURNAL OF SURGERY, 1992, 79 (10) :1050-1053
[4]  
ATTWOOD SEA, 1989, SURGERY, V106, P764
[5]  
ATTWOOD SEA, 1993, ANN SURG, V25, P151
[6]   EFFECT OF PERFUSION OF BILE-SALTS SOLUTIONS INTO ESOPHAGUS OF HIATAL HERNIA PATIENTS AND CONTROLS [J].
BACHIR, GS ;
COLLIS, JL .
THORAX, 1976, 31 (03) :271-277
[7]   Dietary interference with the use of Bilitec to assess bile reflux [J].
Barrett, MW ;
Myers, JC ;
Watson, DI ;
Jamieson, GG .
DISEASES OF THE ESOPHAGUS, 1999, 12 (01) :60-64
[8]  
BARTHLEN W, 1994, DIS ESO, V7, P93
[9]  
BATZRI S, 1991, P SOC EXP BIOL MED, V197, P393
[10]  
BEDIN P, 1993, DIGEST DIS SCI, V38, P1297