Ontogeny of circadian clock gene expression in the pineal and the suprachiasmatic nucleus of chick embryo

被引：31

作者：

Okabayashi, N

Yasuo, S

Watanabe, M

Namikawa, T

Ebihara, S

Yoshimura, T

机构：

[1] Nagoya Univ, Div Biomodeling, Grad Sch Bioagr Sci, Chikusa Ku, Nagoya, Aichi 4648601, Japan

[2] Nagoya Univ, Div Genet & Physiol, Grad Sch Bioagr Sci, Chikusa Ku, Nagoya, Aichi 4648601, Japan

来源：

BRAIN RESEARCH | 2003年 / 990卷 / 1-2期

关键词：

circadian rhythm; clock gene; chick embryo; pineal; suprachiasmatic nucleus; ontogeny;

D O I：

10.1016/S0006-8993(03)03531-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Avian circadian rhythms are regulated by a multiple oscillatory system consisting of the pineal, the suprachiasmatic nucleus (SCN) and the eye. In the present study, ontogeny of circadian clock in the pineal and the SCN of chick embryo was examined using Per2 expression as a marker. A daily rhythmicity of Per2 expression was first detectable at embryonic day (ED) 18 in the pineal and at ED 16 in the SCN under light-dark (LD) cycles. The amplitude of the rhythmicity increased during the development. In contrast, little expression was observed during the development in constant darkness. These results suggest that although circadian clock matures by the end of the embryonic life in chicken, LD cycles are required for the expression of the Per2. (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：231 / 234

页数：4

共 13 条

[1] Spatial and temporal variation of passer Per2 gene expression in two distinct cell groups of the suprachiasmatic hypothalamus in the house sparrow (Passer domesticus)
Abraham, U
Albrecht, U
Gwinner, E
Brandstätter, R
[J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 2002, 16 (03) : 429 - 436
[2] DEVELOPMENT OF REGULATION OF MELATONIN RELEASE IN PINEAL CELLS IN CHICK-EMBRYO
AKASAKA, K
NASU, T
KATAYAMA, T
MURAKAMI, N
[J]. BRAIN RESEARCH, 1995, 692 (1-2) : 283 - 286
[3] Bernard M, 1997, J NEUROCHEM, V68, P213
[4] PINEAL ENZYMES IN CHICKENS - DEVELOPMENT OF DAILY RHYTHMICITY
BINKLEY, S
GELLER, EB
[J]. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1975, 27 (04) : 424 - 429
[5] Rhythms of the pineal N-acetyltransferase mRNA and melatonin concentrations during embryonic and post-embryonic development in chicken
Herichová, I
Zeman, M
Macková, M
Griac, P
[J]. NEUROSCIENCE LETTERS, 2001, 298 (02) : 123 - 126
[6] DEVELOPMENT OF RHYTHMIC MELATONIN SYNTHESIS IN CULTURED PINEAL GLANDS AND PINEAL CELLS ISOLATED FROM CHICK-EMBRYO
LAMOSOVA, D
ZEMAN, M
MACKOVA, M
GWINNER, E
[J]. EXPERIENTIA, 1995, 51 (9-10): : 970 - 975
[7] REPPERT SM, 1995, CIBA F SYMP, V183, P198
[8] Circadian clock genes and photoperiodism: Comprehensive analysis of clock gene expression in the mediobasal hypothalamus, the Suprachiasmatic nucleus, and the pineal gland of Japanese quail under various light schedules
Yasuo, S
Watanabe, M
Okabayashi, N
Ebihara, S
Yoshimura, T
[J]. ENDOCRINOLOGY, 2003, 144 (09) : 3742 - 3748
[9] Effect of melatonin administration on qPer2, qPer3, and qClock gene expression in the suprachiasmatic nucleus of Japanese quail
Yasuo, S
Yoshimura, T
Bartell, PA
Iigo, M
Makino, E
Okabayashi, N
Ebihara, S
[J]. EUROPEAN JOURNAL OF NEUROSCIENCE, 2002, 16 (08) : 1541 - 1546
[10] Molecular analysis of avian circadian clock genes
Yoshimura, T
Suzuki, Y
Makino, E
Suzuki, T
Kuroiwa, A
Matsuda, Y
Namikawa, T
Ebihara, S
[J]. MOLECULAR BRAIN RESEARCH, 2000, 78 (1-2): : 207 - 215

← 1 2 →