Automatic selection of breathing pattern using adaptive support ventilation

被引：79

作者：

Arnal, Jean-Michel ^{[1
]}

Wysocki, Marc ^{[2
]}

Nafati, Cyril ^{[1
]}

Donati, Stephane ^{[1
]}

Granier, Isabelle ^{[1
]}

Corno, Gaelle ^{[1
]}

Durand-Gasselin, Jacques ^{[1
]}

机构：

[1] Hop Font Pre, Serv Reanimat Polyvalente, F-83100 Toulon, France

[2] Hamilton Med, Dept Med Res, Bonaduz, Switzerland

来源：

INTENSIVE CARE MEDICINE | 2008年 / 34卷 / 01期

关键词：

adaptive support ventilation; closed-loop ventilation; acute respiratory distress syndrome; chronic obstructive pulmonary disease; mechanical ventilation;

D O I：

10.1007/s00134-007-0847-0

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Objective: In a cohort of mechanically ventilated patients to compare the automatic tidal volume (V (T))-respiratory rate (RR) combination generated by adaptive support ventilation (ASV) for various lung conditions. Design and setting: Prospective observational cohort study in the 11-bed medicosurgical ICU of a general hospital. Patients: 243 patients receiving 1327 days of invasive ventilation on ASV. Measurements: Daily collection of ventilator settings, breathing pattern, arterial blood gases, and underlying clinical respiratory conditions categorized as: normal lungs, ALI/ARDS, COPD, chest wall stiffness, or acute respiratory failure. Results: Overall the respiratory mechanics differed significantly with the underlying conditions. In passive patients ASV delivered different V (T)-RR combinations based on the underlying condition, providing higher V (T) and lower RR in COPD than in ALI/ARDS: 9.3 ml/kg (8.2-10.8) predicted body weight (PBW) and 13 breaths/min (11-16) vs. 7.6 ml/kg (6.7-8.8) PBW and 18 breaths/min (16-22). In patients actively triggering the ventilator the V (T)-RR combinations did not differ between COPD, ALI/ARDS, and normal lungs. Conclusions: ASV selects different V (T)-RR combinations based on respiratory mechanics in passive, mechanically ventilated patients.

引用

页码：75 / 81

页数：7

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