Urticaria following varicella vaccine associated with gelatin allergy

被引:35
作者
Singer, S
Johnson, CE
Mohr, R
Holowecky, C
机构
[1] Case Western Reserve Univ, Sch Med, Dept Pediat, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Metrohlth Med Ctr, Cleveland, OH 44106 USA
[3] Case Western Reserve Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Cleveland, OH 44106 USA
[4] Univ Colorado, Sch Med, Dept Pediat, Denver, CO USA
关键词
varicella vaccine; gelatin; urticaria;
D O I
10.1016/S0264-410X(98)00209-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
An uncommon reaction to varicella vaccine has been urticaria. Based on two reports of urticaria believed to be due to gelatin in recipients of measles-mumps-rubella vaccine, we suspected gelatin as the cause of generalized urticaria in two children after varicella vaccination. Intradermal testing with gelatin yielded a wheal and flare reaction in both children. We conclude that children known to be allergic to gelatin should not receive Oka/Merck varicella Vaccine (VARIVAX(R)). (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:327 / 329
页数:3
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