The parasite clearance curve

被引:149
作者
White, N. J. [1 ,2 ]
机构
[1] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok, Thailand
[2] Univ Oxford, Churchill Hosp, Ctr Trop Med, Oxford, England
来源
MALARIA JOURNAL | 2011年 / 10卷
基金
英国惠康基金;
关键词
SEVERE FALCIPARUM-MALARIA; PLASMODIUM-FALCIPARUM; ARTEMISININ RESISTANCE; AFRICAN CHILDREN; WESTERN CAMBODIA; CEREBRAL MALARIA; CELL COUNTS; IN-VIVO; DENSITY; QUININE;
D O I
10.1186/1475-2875-10-278
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Parasite clearance rates are important measures of anti-malarial drug efficacy. They are particularly important in the assessment of artemisinin resistance. The slope of the log-linear segment in the middle of the parasite clearance curve has the least inter-individual variance and is the focus of therapeutic assessment. The factors affecting parasite clearance are reviewed. Methods of presentation and the approaches to analysis are discussed.
引用
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页数:8
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