Is energy deficiency good in moderation?

被引：11

作者：

Freyer, Christoph ^{[1
]}

Larsson, Nils-Goran ^{[1
]}

机构：

[1] Karolinska Inst, Dept Lab Med, S-14186 Huddinge, Sweden

来源：

CELL | 2007年 / 131卷 / 03期

关键词：

D O I：

10.1016/j.cell.2007.10.027

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this issue, Pospisilik et al. (2007) demonstrate that a reduction in mitochondrial oxidative phosphorylation protects mice against obesity and diabetes. This finding suggests that the moderate deficiency in oxidative phosphorylation that is observed in peripheral tissues of insulin-resistant humans is not a causative factor in diabetes but may instead be a compensatory response.

引用

页码：448 / 450

页数：3

共 9 条

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