Cutaneous sympathetic function and cardiovascular function in patients with progressive supranuclear palsy and Parkinson's disease

被引：26

作者：

Kikkawa, Y ^{[1
]}

Asahina, M ^{[1
]}

Suzuki, A ^{[1
]}

Hattori, T ^{[1
]}

机构：

[1] Chiba Univ, Sch Med, Dept Neurol, Chuo Ku, Chiba 2608670, Japan

来源：

PARKINSONISM & RELATED DISORDERS | 2003年 / 10卷 / 02期

关键词：

progressive supranuclear palsy; Parkinson's disease; autonomic nervous system; sudomotor function; skin vasomotor function;

D O I：

10.1016/S1353-8020(03)00109-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Some procedures, such as deep inspiration, increase sweat output (SSwR; sympathetic sweat response) and reduce cutaneous blood flow (SVR; skin vasomotor reflex) on the palm. We investigated SSwR, SVR, and cardiovascular function in 12 patients with progressive supranuclear palsy (PSP), 13 patients with Parkinson's disease (PD), and 9 healthy subjects. In the PSP patients, SSwR was severely diminished, whereas SVR was maintained and cardiovascular function was well preserved. In the PD patients, SSwR was relatively preserved, SVR was maintained, and some patients showed cardiovascular hypofunction. A combination of skin sympathetic and cardiovascular tests may be useful for distinguishing between PD and PSP. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：101 / 106

页数：6

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