Olfactory receptor database: a database of the largest eukaryotic gene family

被引:21
作者
Skoufos, E
Healy, MD
Singer, MS
Nadkarni, PM
Miller, PL
Shepherd, GM
机构
[1] Yale Univ, Sch Med, Ctr Med Informat, New Haven, CT 06511 USA
[2] Yale Univ, Sch Med, Neurobiol Sect, New Haven, CT 06511 USA
[3] Bristol Myers Squibb Co, Div Res, Wallingford, CT USA
关键词
D O I
10.1093/nar/27.1.343
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Olfactory Receptor Database (ORDB) is a WWW-accessible database that stores data on Olfactory Receptor-like molecules (ORs) and has been open to the public since June 1996. it contains a public and a private area. The public area includes published DNA and protein sequence data for ORs, links to OR models and data on their expression, chromosomal localization and source organism, as well as (i) links to bibliography through PubMed and (ii) interactive WWW-based tools, such as BLAST homology searching. The private area functions as a service to laboratories that are actively cloning receptors, Source laboratories enter the sequences of the receptor clones they have characterized to the private database and can search for identical or near identical OR sequences in both public and private databases. If another laboratory has cloned and deposited an identical or closely matching sequence there are means for communication between the laboratories to help avoid duplication of work. ORDB is available via the WWW at http://crepe.med.yale.edu/ORDB/HTML.
引用
收藏
页码:343 / 345
页数:3
相关论文
共 14 条
  • [1] BASIC LOCAL ALIGNMENT SEARCH TOOL
    ALTSCHUL, SF
    GISH, W
    MILLER, W
    MYERS, EW
    LIPMAN, DJ
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) : 403 - 410
  • [2] A NOVEL MULTIGENE FAMILY MAY ENCODE ODORANT RECEPTORS - A MOLECULAR-BASIS FOR ODOR RECOGNITION
    BUCK, L
    AXEL, R
    [J]. CELL, 1991, 65 (01) : 175 - 187
  • [3] Olfactory receptor database (ORDB): A resource for sharing and analyzing published and unpublished data
    Healy, MD
    Smith, JE
    Singer, MS
    Nadkarni, PM
    Skoufos, E
    Miller, PL
    Shepherd, GM
    [J]. CHEMICAL SENSES, 1997, 22 (03) : 321 - 326
  • [4] GPCRDB:: an information system for G protein-coupled receptors
    Horn, F
    Weare, J
    Beukers, MW
    Hörsch, S
    Bairoch, A
    Chen, W
    Edvardsen, O
    Campagne, F
    Vriend, G
    [J]. NUCLEIC ACIDS RESEARCH, 1998, 26 (01) : 275 - 279
  • [5] KOLAKOWSKI LF, 1994, RECEPTOR CHANNEL, V2, P1
  • [6] Kristiansen K, 1996, PROTEINS, V26, P81, DOI 10.1002/(SICI)1097-0134(199609)26:1<81::AID-PROT8>3.3.CO
  • [7] 2-R
  • [8] SHEPHERD GM, 1997, NEUROINFORMATICS OVE
  • [9] SINGER MS, 1995, RECEPTOR CHANNEL, V3, P89
  • [10] MOLECULAR MODELING OF LIGAND-RECEPTOR INTERACTIONS IN THE OR5 OLFACTORY RECEPTOR
    SINGER, MS
    SHEPHERD, GM
    [J]. NEUROREPORT, 1994, 5 (10) : 1297 - 1300