alpha-Azidoesters as divergent intermediates for combinatorial generation of glucofuranose libraries of novel N-linked glycopeptides

被引：22

作者：

Brandstetter, TW

delaFuente, C

Kim, YH

Cooper, RI

Watkin, DJ

Oikonomakos, NG

Johnson, LN

Fleet, GWJ

机构：

[1] OXFORD CTR MOL SCI,DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

[2] UNIV OXFORD,CHEM CRYSTALLOG LAB,OXFORD OX1 3PD,ENGLAND

[3] NATL HELLEN RES FDN,ATHENS 11635,GREECE

[4] LAB MOL BIOPHYS,OXFORD OX1 3QU,ENGLAND

来源：

TETRAHEDRON | 1996年 / 52卷 / 32期

关键词：

D O I：

10.1016/0040-4020(96)00594-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Epimeric azidoesters containing a glucofuranosyl moiety are readily prepared from glucoheptonolactone and may be reduced to corresponding aminoesters; such compounds may be useful intermediates for the generation of combinatorial libraries of glucofuranose mimics and of spiroderivatives of glucofuranose at the anomeric position. The X-ray crystal structure of methyl 2-amino-2-deoxy-3,4-di-O-tert-butyldimethylsilyl-6,7-O-isopropylidene-beta-D-gluco-2-heptulofuranoate is reported. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：10711 / 10720

页数：10

共 20 条

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