The genomic structure of SYCP3, a meiosis-specific gene encoding a protein of the chromosome core

被引：21

作者：

Botelho, RJ ^{[1
]}

DiNicolo, L ^{[1
]}

Tsao, N ^{[1
]}

Karaiskakis, A ^{[1
]}

Tarsounas, M ^{[1
]}

Moens, PB ^{[1
]}

Pearlman, RE ^{[1
]}

机构：

[1] York Univ, Dept Biol, N York, ON M3J 1P3, Canada

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2001年 / 1518卷 / 03期

基金：

加拿大自然科学与工程研究理事会;

关键词：

meiosis; synaptonemal complex; promoter; gene structure; chromosome core;

D O I：

10.1016/S0167-4781(01)00171-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

SYCP3 localizes to the lateral elements of the synaptonemal complex and is essential for male meiosis. The genomic structure of SYCP3 consists of nine exons spanning approximately 14 kb. In mouse and rat, but not in hamster. the putative translation start of SYCP3 is present in the first exon. The putative promoter of SYCP3 was also cloned and shown to drive transcription of a reporter gene in somatic cells. (C) 2001 Elsevier Science B.V, All rights reserved.

引用

页码：294 / 299

页数：6

共 16 条

[1]

DOBSON MJ, 1994, J CELL SCI, V107, P2749

[2] The mouse synaptonemal complex protein gene Sycp3 maps to band C of Chromosome 10 [J].