Adult respiratory distress syndrome with increased serum and bronchoalveolar lavage fluid levels of squamous cell carcinoma-related antigen

被引:10
作者
Ashitani, J
Mukae, H
Ihiboshi, H
Taniguchi, H
Mashimoto, H
Matsukura, S
机构
[1] Third Dept. of Internal Medicine, Miyazaki Medical College, Kihara, Miyazaki 889-16
关键词
adult respiratory distress syndrome (ARDS); neutrophil elastase; squamous cell carcinoma-related antigen (SCC); interleukin (IL)-8;
D O I
10.2169/internalmedicine.35.497
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report a case with adult respiratory distress syndrome (ARDS) associated with increased levels of squamous cell carcinoma-related antigen (SCC) in the serum and bronchoalveolar lavage fluid (BALF). ARDS was likely induced by ibuprofen, based on the presence of pancytopenia and a weakly positive drug lymphocyte stimulating test (DLST). High serum and BALF levels of interleukin (IL)-8, neutrophil elastase as well as SCC were detected, Corticosteroid therapy resulted in clinical improvement, resolution of pulmonary infiltrates on chest roentgenogram and normalization of serum and BALF levels of IL-8, neutrophil elastase and SCC.
引用
收藏
页码:497 / 501
页数:5
相关论文
共 18 条
[1]  
[Anonymous], AM REV RESP DIS
[2]   ALTERATIONS OF GAS-EXCHANGE APPARATUS IN ADULT RESPIRATORY INSUFFICIENCY ASSOCIATED WITH SEPTICEMIA [J].
BACHOFEN, M ;
WEIBEL, ER .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1977, 116 (04) :589-615
[3]  
Bando M, 1994, Nihon Kyobu Shikkan Gakkai Zasshi, V32, P95
[4]   SQUAMOUS-CELL CARCINOMA ANTIGEN (SCC AG) IN THE DIAGNOSIS AND PROGNOSIS OF LUNG-CANCER [J].
DECOS, JS ;
MASA, F ;
DELACRUZ, JL ;
DISDIER, C ;
VERGARA, C .
CHEST, 1994, 105 (03) :773-776
[5]  
IDELL S, 1985, AM REV RESPIR DIS, V132, P1098
[6]  
KATO H, 1987, RINSHO KENSA, V31, P430
[7]  
KATSURAGI M, 1985, Kaku Igaku, V22, P1809
[8]   MECHANISM OF MAMMALIAN-CELL LYSIS MEDIATED BY PEPTIDE DEFENSINS - EVIDENCE FOR AN INITIAL ALTERATION OF THE PLASMA-MEMBRANE [J].
LICHTENSTEIN, A .
JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (01) :93-100
[9]   ELEVATED LEVELS OF NAP-1/INTERLEUKIN-8 ARE PRESENT IN THE AIRSPACES OF PATIENTS WITH THE ADULT RESPIRATORY-DISTRESS SYNDROME AND ARE ASSOCIATED WITH INCREASED MORTALITY [J].
MILLER, EJ ;
COHEN, AB ;
NAGAO, S ;
GRIFFITH, D ;
MAUNDER, RJ ;
MARTIN, TR ;
WEINERKRONISH, JP ;
STICHERLING, M ;
CHRISTOPHERS, E ;
MATTHAY, MA .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1992, 146 (02) :427-432
[10]   ELEVATION OF TUMOR-ASSOCIATED CARBOHYDRATE ANTIGENS IN PATIENTS WITH DIFFUSE PANBRONCHIOLITIS [J].
MUKAE, H ;
HIROTA, M ;
KOHNO, S ;
KOMORI, K ;
FUKUSHIMA, K ;
HIRATANI, K ;
KADOTA, JI ;
HARA, K .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 148 (03) :744-751