Hierridin B and 2,4-dimethoxy-6-heptadecyl-phenol, secondary metabolites from the cyanobacterium Phormidium ectocarpi with antiplasmodial activity

被引：55

作者：

Papendorf, O ^{[1
]}

König, GM ^{[1
]}

Wright, AD ^{[1
]}

机构：

[1] Tech Univ Braunschweig, Inst Pharmaceut Biol, D-38106 Braunschweig, Germany

来源：

PHYTOCHEMISTRY | 1998年 / 49卷 / 08期

关键词：

cyanobacteria; biological activity; antimalaria; Phormidium; aromatic; lipids;

D O I：

10.1016/S0031-9422(98)00440-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bioassay guided fractionation of the lipophilic extract of the marine cyanobacterium Phormidium ectocarpi yielded a new natural product hierridin B and the previously described compound 2,4-dimethoxy-6-heptadecyl-phenol. Both structures were secured by extensive spectroscopic analysis (1D and 2D NMR, MS, GC-MS, IR). The isolate (mixture) showed antiplasmodial activity towards Plasmodium falciparum. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：2383 / 2386

页数：4

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