Predictors of prognosis in patients with peripartum cardiomyopathy

Objectives: To evaluate the long-term follow-up results of patients with peripartum cardiomyopathy and assess the echocardiographic findings relating to prognosis at time of diagnosis. Methods: Thirty-three patients diagnosed with peripartum cardiomyopathy and hospitalized between 1995 and 2007 were analyzed. Initial echocardiographic data were recorded and long-term clinical status was evaluated. Results: Eight (24%) patients recovered completely, 10 (30%) died, 2 (6%) underwent heart transplants, and 13 (39%) were left with persistent left ventricular dysfunction. Cut-off values for initial left ventricular end-systolic diameter (<= 5.5 cm) and left ventricular ejection fraction (> 27%) were obtained from patients who had completely recovered. Conclusion: Cut-off values for initial left ventricular ejection fraction of > 27% and left ventricular end-systolic diameter of <= 5.5 cm may predict recovery of left ventricle function. (c) 2007 International Journal of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.