Communication in a protein stack:: Electron transfer between cytochrome c and bilirubin oxidase within a polyelectrolyte multilayer

被引：61

作者：

Dronov, Roman ^{[2
]}

Kurth, Dirk G. ^{[2
,3
]}

Moehwald, Helmuth ^{[2
]}

Scheller, Frieder W. ^{[4
]}

Lisdat, Fred ^{[1
]}

机构：

[1] Wildau Univ Appl Sci, D-15745 Wildau, Germany

[2] Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany

[3] Natl Inst Mat Sci, Tsukuba, Ibaraki 3050044, Japan

[4] Univ Potsdam, D-14476 Potsdam, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 16期

关键词：

cytochrome c; electron transfer; enzymes; polyelectrolytes; self-assembly;

D O I：

10.1002/anie.200704049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Assemblies of proteins and enzymes can serve as a model for mimicking biological signal transfer. A polyelectrolyte multilayer (see picture) of an electron-transfer protein (cytochrome c, red) and a copper enzyme (bilirubin oxidase, blue) has catalytic properties for four-electron oxygen reduction. The proposed architecture guarantees efficient protein-protein interaction without an additional redox mediator. (Figure Presented) © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3000 / 3003

页数：4

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