Flow-injection analysis of two fluoquinolones by the sensitizing effect of terbium(III) on chemiluminescence of the potassium permanganate-sodium sulfite system

被引：60

作者：

Yi, L

Zhao, HC ^{[1
]}

Chen, S

Jin, LP

Zheng, DD

Wu, ZL

机构：

[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

[2] Beijing Normal Univ, Analyt & Testing Ctr, Beijing 100875, Peoples R China

来源：

TALANTA | 2003年 / 61卷 / 03期

基金：

中国国家自然科学基金;

关键词：

chemiluminescence; enoxacin; ofloxacin; terbium(III);

D O I：

10.1016/S0039-9140(03)00301-1

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A simple, rapid and sensitive method for the determination of two fluoquinolones (FQs), enoxacin (ENX) and ofloxacin (OFLX) is described by using flow injection analysis with potassium permanganate-sodium sulfite chemiluminescence detection. The calibration graphs for ENX and OFLX are linear in the range of 8.0 x 10(-10) 1.0 X 10(-5) and 1.0 X 10(-9)1.0 X 10(-6) mol l(-1), respectively. The 3sigma limits of detection are 2.4 x 10(-10) mol l(-1) for ENX and 5.6 x 10(-10) mol l(-1) for OFLX. The method is applied satisfactorily to the determination of the two FQs in dosage form and urine sample. The possible mechanism is also proposed. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：403 / 409

页数：7

共 25 条

[1] DETERMINATION OF OFLOXACIN IN PHARMACEUTICAL FORMS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND DERIVATIVE UV-SPECTROPHOTOMETRY [J].