MicroRNAs and cancer

被引：119

作者：

Dalmay, T. ^{[1
]}

机构：

[1] Univ E Anglia, Sch Biol Sci, Norwich NR4 7TJ, Norfolk, England

来源：

JOURNAL OF INTERNAL MEDICINE | 2008年 / 263卷 / 04期

关键词：

cancer; molecular biology; miRNA;

D O I：

10.1111/j.1365-2796.2008.01926.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The Nobel Prize in Medicine and Physiology was awarded to the RNA interference (RNAi) field in 2006 because of the huge therapeutic potential this technique harbours. However, the RNAi technology is based on a natural mechanism that utilizes short noncoding RNA molecules (microRNAs) to regulate gene expression. This paper reviews our current knowledge about microRNAs focusing on their involvement in cancer and their potential as diagnostics and therapeutics.

引用

页码：366 / 375

页数：10

共 58 条

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