SbCl5-wet acetonitrile:: a new system for chemoselective O-desilylation

被引：24

作者：

Glória, PMC

Prabhakar, S

Lobo, AM

Gomes, MJS

机构：

[1] Univ Nova Lisboa, CQFB,REQUIMTE, Dept Quim, Seccao Quim Organ Aplicada, P-2829 Monte De Caparica, Portugal

[2] Univ Nova Lisboa, SINTOR, P-2829 Monte De Caparica, Portugal

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 49期

关键词：

D O I：

10.1016/j.tetlet.2003.09.191

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new efficient method for deprotection of TBDMS derivatives of phenols, primary alcohols, carboxylic acids and secondary amines, consisting of SbCl5 and MeCN with 0.1% water (w/v), is reported. It effects inter alia desilylation of a CH2OTBDMS group in the presence of a ketal function. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8819 / 8821

页数：3

共 7 条

[1] PROTECTION OF HYDROXYL GROUPS AS TERT-BUTYLDIMETHYLSILYL DERIVATIVES [J].