Fundamental role of the fostriecin unsaturated lactone and implications for selective protein phosphatase inhibition

被引：117

作者：

Buck, SB

Hardouin, C

Ichikawa, S

Soenen, DR

Gauss, CM

Hwang, I

Swingle, MR

Bonness, KM

Honkanen, RE

Boger, DL

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

[3] Univ S Alabama, Coll Med, Dept Biochem & Mol Biol, Mobile, AL 36688 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 51期

关键词：

D O I：

10.1021/ja038672n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：15694 / 15695

页数：2

共 31 条

[1] Determination of the relative and absolute stereochemistry of fostriecin (CI-920) [J].

Boger, DL ;

Hikota, M ;

Lewis, BM .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (06) :1748-1753

[2] Total synthesis of fostriecin (CI-920) [J].

Boger, DL ;

Ichikawa, S ;

Zhong, W .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (18) :4161-4167

[3] INHIBITION OF TYPE-II TOPOISOMERASE BY FOSTRIECIN [J].

BORITZKI, TJ ;

WOLFARD, TS ;

BESSERER, JA ;

JACKSON, RC ;

FRY, DW .

BIOCHEMICAL PHARMACOLOGY, 1988, 37 (21) :4063-4068

[4]

Chavez DE, 2001, ANGEW CHEM INT EDIT, V40, P3667, DOI 10.1002/1521-3773(20011001)40:19<3667::AID-ANIE3667>3.0.CO

[5]

2-6

[6]

Cheng AY, 1998, CANCER RES, V58, P3611

[7] Importance of the β12-β13 loop in protein phosphatase-1 catalytic subunit for inhibition by toxins and mammalian protein inhibitors [J].

Connor, JH ;

Kleeman, T ;

Barik, S ;

Honkanen, RE ;

Shenolikar, S .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (32) :22366-22372

[8] Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin [J].

de Jong, RS ;

Mulder, NH ;

Uges, DRA ;

Sleijfer, DT ;

Höppener, FJP ;

Groen, HJM ;

Willemse, PHB ;

van der Graaf, WTA ;

de Vries, EGE .

BRITISH JOURNAL OF CANCER, 1999, 79 (5-6) :882-887

[9] Fostriecin: A review of the preclinical data [J].

deJong, RS ;

deVries, EGE ;

Mulder, NH .

ANTI-CANCER DRUGS, 1997, 8 (05) :413-418

[10] CRYSTAL-STRUCTURE OF THE CATALYTIC SUBUNIT OF HUMAN PROTEIN PHOSPHATASE-1 AND ITS COMPLEX WITH TUNGSTATE [J].

EGLOFF, MP ;

COHEN, PTW ;

REINEMER, P ;

BARFORD, D .

JOURNAL OF MOLECULAR BIOLOGY, 1995, 254 (05) :942-959

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