Genetic analysis of the capsule locus of Haemophilus influenzae serotype f

被引：32

作者：

Satola, SW

Schirmer, PL

Farley, MM

机构：

[1] Atlanta VA med Ctr, Med Res Serv 151, Decatur, GA 30033 USA

[2] Emory Univ, Sch Med, Dept Med, Decatur, GA 30033 USA

来源：

INFECTION AND IMMUNITY | 2003年 / 71卷 / 12期

关键词：

D O I：

10.1128/IAI.71.12.7202-7207.2003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 19-kb DNA region containing genes involved in the biosynthesis of the capsule of Haemophilus influenzae serotype f (Hif) has been cloned and characterized. The Hif cap locus organization is typical of group H capsule biosynthetic loci found in other H. influenzae serotype b bacteria and other gram-negative bacteria. However, the Hif cap locus was not associated with an IS1016 element. Three new open reading frames, Fcs1, Fcs2, and Fcs3, were identified in the Hif capsule-specific region II. The chromosomal location of the Hif cap locus and the organization of the flanking sequences differed significantly from previously described division I H. influenzae serotypes.

引用

页码：7202 / 7207

页数：6

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