Pathogenesis and management of hypertension after kidney transplantation

被引：44

作者：

Chatzikyrkou, Christos ^{[1
]}

Menne, Jan ^{[1
]}

Gwinner, Wilfried ^{[1
]}

Schmidt, Bernhard M. ^{[1
]}

Lehner, Frank ^{[2
]}

Blume, Cornelia ^{[1
]}

Schwarz, Anke ^{[1
]}

Haller, Hermann ^{[1
]}

Schiffer, Mario ^{[1
]}

机构：

[1] Hannover Med Sch, Dept Med, Div Nephrol & Hypertens, Integrated Res & Treatment Ctr Transplantat IFB T, D-30625 Hannover, Germany

[2] Hannover Med Sch, Dept Med, Dept Gen Visceral & Transplantat Surg, Integrated Res & Treatment Ctr Transplantat IFB T, D-30625 Hannover, Germany

来源：

JOURNAL OF HYPERTENSION | 2011年 / 29卷 / 12期

关键词：

posttransplant hypertension; target blood pressure; immunosuppression; calcineurin inhibitors; renin angiotensin system; BLOOD-PRESSURE CONTROL; DELAYED GRAFT FUNCTION; CONVERTING ENZYME-INHIBITOR; SYMPATHETIC-NERVE ACTIVITY; STAGE RENAL-DISEASE; LONG-TERM OUTCOMES; CARDIOVASCULAR OUTCOMES; PATIENT SURVIVAL; ARTERIAL-HYPERTENSION; INCREASED MORTALITY;

D O I：

10.1097/HJH.0b013e32834bd1e7

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Arterial hypertension is frequently encountered after renal transplantation and is associated not only with increased cardiovascular complications but also with decreased allograft survival. Adequate blood pressure control is, thus, as essential as immunologic surveillance for the long-term transplant care. Nevertheless, randomized control trials assessing treatment targets in these patients are not available and most of the evidence comes from studies in patients with native chronic kidney disease or the general population. In this regard, the renal transplant recipient is treated according to recommendations that are applicable to nontransplanted individuals at high cardiovascular risk. However, the accepted treatment targets for the nontransplanted population are recently being disputed and this makes the management of posttransplant hypertension ;even more challenging. J Hypertens 29: 2283-2294 (C) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

引用

页码：2283 / 2294

页数：12

共 118 条

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