Hyperplastic callus formation in osteogenesis imperfecta type V: follow-up of three generations over ten years

被引:16
作者
Cheung, Moira S. [2 ]
Azouz, E. Michel [2 ]
Glorieux, Francis H. [2 ]
Rauch, Frank [1 ,2 ]
机构
[1] Shriners Hosp Children, Genet Unit, Montreal, PQ H3G 1A6, Canada
[2] McGill Univ, Montreal, PQ, Canada
关键词
fractures; genetic disorder; hyperplastic callus; osteogenesis imperfecta; radiographs;
D O I
10.1007/s00256-007-0441-0
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Hyperplastic callus (HPC) formation is a prominent feature of osteogenesis imperfecta (OI) type V; however, little is known about its long-term outcome. In this case report we describe the occurrence, appearance and course of a femoral HPC in a patient with OI type V during 10 years of follow-up. Radiographs of HPC in this child were compared and contrasted with HPC formation in the femur of his father and paternal grandfather, who also were affected with OI type V. This case report makes it clear that HPC can lead to significant morbidity, not only in the acute phase but also long term as a result of residual alteration in bone architecture.
引用
收藏
页码:465 / 467
页数:3
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