Building excitatory and inhibitory synapses: Balancing neuroligin partnerships

被引：111

作者：

Levinson, JN

El-Husseini, A

机构：

[1] Univ British Columbia, Dept Psychiat, Vancouver, BC V6T 1Z3, Canada

[2] Univ British Columbia, Brain Res Ctr, Vancouver, BC V6T 1Z3, Canada

来源：

NEURON | 2005年 / 48卷 / 02期

关键词：

D O I：

10.1016/j.neuron.2005.09.017

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Processing of neural information is thought to occur by integration of excitatory and inhibitory synaptic inputs. As such, precise control mechanisms must exist to maintain an appropriate balance between each synapse type. Recent findings indicate that neuroligins and their synaptic binding partners modulate the development of both excitatory and inhibitory synapses. Here we highlight these findings and discuss a mechanism potentially involved in controlling the balance between excitation and inhibition.

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页码：171 / 174

页数：4

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