Laboratory testing for heparin-induced thrombocytopenia: a conceptual framework and implications for diagnosis

被引:128
作者
Warkentin, T. E. [1 ,2 ]
Greinacher, A. [3 ]
Gruel, Y. [4 ]
Aster, R. H. [5 ,6 ]
Chong, B. H. [7 ,8 ]
机构
[1] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada
[2] McMaster Univ, Dept Med, Hamilton, ON, Canada
[3] Ernst Moritz Arndt Univ Greifswald, Dept Immunol & Transfus Med, Greifswald, Germany
[4] Hop Trousseau, Dept Hematol, Tours, France
[5] Med Coll Wisconsin, Blood Ctr Wisconsin, Blood Res Inst, Milwaukee, WI 53226 USA
[6] Med Coll Wisconsin, Dept Med, Milwaukee, WI 53226 USA
[7] Univ New S Wales, St George Clin Sch, Dept Med, Sydney, NSW, Australia
[8] St George Hosp, Sydney, NSW, Australia
关键词
PERFORMANCE-CHARACTERISTICS; ANTIBODIES; IMMUNOASSAYS; SCORE; IGG; ASSAY; HIT;
D O I
10.1111/j.1538-7836.2011.04536.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2498 / 2500
页数:3
相关论文
共 26 条
[1]  
AMIRAL J, 1992, THROMB HAEMOSTASIS, V68, P95
[2]   Current concepts - Drug-induced immune thrombocytopenia [J].
Aster, Richard H. ;
Bougie, Daniel W. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (06) :580-587
[3]   Prospective evaluation of PF4/heparin immunoassays for the diagnosis of heparin-induced thrombocytopenia [J].
Bakchoul, T. ;
Giptner, A. ;
Najaoui, A. ;
Bein, G. ;
Santoso, S. ;
Sachs, U. J. H. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 (08) :1260-1265
[4]   Performance characteristics of two commercially available IgG-specific immunoassays in the assessment of heparin-induced thrombocytopenia (HIT) [J].
Bakchoul, Tamam ;
Giptner, Astrid ;
Bein, Gregor ;
Santoso, Sentot ;
Sachs, Ulrich J. H. .
THROMBOSIS RESEARCH, 2011, 127 (04) :345-348
[5]  
Chong Beng H, 2004, Expert Rev Cardiovasc Ther, V2, P547, DOI 10.1586/14779072.2.4.547
[6]  
CHONG BH, 1993, THROMB HAEMOSTASIS, V69, P344
[7]   HEPARIN-INDUCED THROMBOCYTOPENIA - MECHANISM OF INTERACTION OF THE HEPARIN-DEPENDENT ANTIBODY WITH PLATELETS [J].
CHONG, BH ;
FAWAZ, I ;
CHESTERMAN, CN ;
BERNDT, MC .
BRITISH JOURNAL OF HAEMATOLOGY, 1989, 73 (02) :235-240
[8]   The HIT Expert Probability (HEP) Score: a novel pre-test probability model for heparin-induced thrombocytopenia based on broad expert opinion [J].
Cuker, A. ;
Arepally, G. ;
Crowther, M. A. ;
Rice, L. ;
Datko, F. ;
Hook, K. ;
Propert, K. J. ;
Kuter, D. J. ;
Ortel, T. L. ;
Konkle, B. A. ;
Cines, D. B. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2010, 8 (12) :2642-2650
[9]   Heparin-induced thrombocytopenia: a prospective study on the incidence, platelet-activating capacity and clinical significance of antiplatelet factor 4/heparin antibodies of the IgG, IgM, and IgA classes [J].
Greinacher, A. ;
Juhl, D. ;
Strobel, U. ;
Wessel, A. ;
Lubenow, N. ;
Selleng, K. ;
Eichler, P. ;
Warkentin, T. E. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2007, 5 (08) :1666-1673
[10]   Heparin-induced thrombocytopenia: towards standardization of platelet factor 4/heparin antigen tests [J].
Greinacher, A. ;
Ittermann, T. ;
Bagemuehl, J. ;
Althaus, K. ;
Fuerll, B. ;
Selleng, S. ;
Lubenow, N. ;
Schellong, S. ;
Sheppard, J. I. ;
Warkentin, T. E. .
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2010, 8 (09) :2025-2031