Microinfarcts, brain atrophy, and cognitive function: The Honolulu Asia Aging Study Autopsy Study

被引：144

作者：

Launer, Lenore J. ^{[1
]}

Hughes, Timothy M. ^{[2
]}

White, Lon R. ^{[3
,4
]}

机构：

[1] NIA, LEDB, NIH, Bethesda, MD 20892 USA

[2] Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA

[3] Univ Hawaii, Dept Geriatr Med, John A Burns Sch Med, Honolulu, HI 96822 USA

[4] Kuakini Med Ctr, Honolulu Asia Aging Study, Honolulu, HI USA

来源：

ANNALS OF NEUROLOGY | 2011年 / 70卷 / 05期

关键词：

ALZHEIMERS-DISEASE; DEMENTIA;

D O I：

10.1002/ana.22520

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: This study was untaken to investigate the association of micro brain infarcts (MBIs) with antemortem global cognitive function (CF), and whether brain weight (BW) and Alzheimer lesions (neurofibrillary tangles [NFTs] or neuritic plaques [NPs]) mediate the association.

引用

收藏

页码：774 / 780

页数：7

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