Immunity against cancer: lessons learned from melanoma

被引：157

作者：

Houghton, AN

Gold, JS

Blachere, NE

机构：

[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[2] Cornell Univ, Weill Med Sch, New York, NY 10021 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2001年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(00)00195-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Most major advances in human cancer immunology and immunotherapy have come from studies in melanoma. We are beginning to understand the immune repertoire of T cells and antibodies that are active against melanoma, with recent glimpses of the CD4(+) T cell repertoire. The view of what the immune system can see is extending to mutations and parts of the genome that are normally invisible.

引用

页码：134 / 140

页数：7

共 59 条

[1] ALBINO AP, 1992, ONCOGENE, V7, P2315
[2] An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillance in metastatic lesions
Anichini, A
Molla, A
Mortarini, R
Tragni, G
Bersani, I
Di Nicola, M
Gianni, AM
Pilotti, S
Dunbar, R
Cerundolo, V
Parmiani, G
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (05) : 651 - 667
[3] Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma
Bloom, MB
PerryLalley, D
Robbins, PF
Li, Y
ElGamil, M
Rosenberg, SA
Yang, JC
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 185 (03) : 453 - 459
[4] Coupling and uncoupling of tumor immunity and autoimmunity
Bowne, WB
Srinivasan, R
Wolchok, JD
Hawkins, WG
Blachere, NE
Dyall, R
Lewis, JJ
Houghton, AN
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (11) : 1717 - 1722
[5] Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4+ T lymphocytes
Chaux, P
Vantomme, V
Stroobant, V
Thielemans, K
Corthals, J
Luiten, R
Eggermont, AMM
Boon, T
van der Bruggen, P
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (05) : 767 - 777
[6] A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening
Chen, YT
Scanlan, MJ
Sahin, U
Tureci, O
Gure, AO
Tsang, SL
Williamson, B
Stockert, E
Pfreundschuh, M
Old, LJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (05) : 1914 - 1918
[7] Chiari R, 2000, CANCER RES, V60, P4855
[8] Fc receptors are required in passive and active immunity to melanoma
Clynes, R
Takechi, Y
Moroi, Y
Houghton, A
Ravetch, JV
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (02) : 652 - 656
[9] Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
Clynes, RA
Towers, TL
Presta, LG
Ravetch, JV
[J]. NATURE MEDICINE, 2000, 6 (04) : 443 - 446
[10] Self-tolerance to the murine homologue of a tyrosinase-derived melanoma antigen: Implications for tumor immunotherapy
Colella, TA
Bullock, TNJ
Russell, LB
Mullins, DW
Overwijk, WW
Luckey, CJ
Pierce, RA
Restifo, NP
Engelhard, VH
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 2000, 191 (07) : 1221 - 1231

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