Synthesis of trisphaeridine and norchelerythrine through palladium-catalyzed aryl-aryl coupling reaction

被引：101

作者：

Harayama, T ^{[1
]}

Akamatsu, H ^{[1
]}

Okamura, K ^{[1
]}

Miyagoe, T ^{[1
]}

Akiyama, T ^{[1
]}

Abe, H ^{[1
]}

Takeuchi, Y ^{[1
]}

机构：

[1] Okayama Univ, Fac Pharmaceut Sci, Okayama 7008530, Japan

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 05期

关键词：

D O I：

10.1039/b008683p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Total syntheses of trisphaeridine (3) and norchelerythrine (4), fully aromatized benzo[c]phenanthridine alkaloids, were accomplished via the internal aryl-aryl coupling reaction of halo amides protected by a methoxymethyl group with the palladium reagent, followed by reduction with lithium aluminium hydride and treatment with hydrochloric acid.

引用

页码：523 / 528

页数：6

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