A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease

被引：290

作者：

Zadikoff, Cindy ^{[1
,2
]}

Fox, Susan H. ^{[1
]}

Tang-Wai, David F. ^{[1
]}

Thomsen, Teri ^{[1
]}

de Bie, Rob M. A. ^{[1
,3
]}

Wadia, Pettarusup ^{[1
]}

Miyasaki, Janis ^{[1
]}

Duff-Canning, Sarah ^{[1
]}

Lang, Anthony E. ^{[1
]}

Marras, Connie ^{[1
]}

机构：

[1] Univ Toronto, Toronto Western Hosp, Morton & Gloria Shulman Movement Disorders Ctr, Div Neurol, Toronto, ON M5T 2S8, Canada

[2] NW Univ, Parkisons Dis & Movement Disorders Ctr, Dept Neurol, Chico, CA USA

[3] Acad Med Ctr, Dept Neurol, Amsterdam, Netherlands

来源：

MOVEMENT DISORDERS | 2008年 / 23卷 / 02期

关键词：

Parkinson's disease; dementia; mild cognitive impairment; MMSE; MoCA;

D O I：

10.1002/mds.21837

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a broader range of domains frequently affected in PD. The scores on the MMSE and the MoCA were compared in 88 patients with PD. A pronounced ceiling effect was observed with the MMSE but not with the MoCA. The range and standard deviation of scores was larger with the MoCA(7-30, 4.26) than with the MMSE(16-30, 2.55). The percentage of subjects scoring below a cutoff of 26/30 (used by others to detect mild cognitive impairment) was higher on the MoCA (32%) than on the MMSE (11%)(P < 0.000002). Compared to the MMSE, the MoCA may be a more sensitive tool to identify early cognitive impairment in PD. (C) 2007 Movement Disorder Society.

引用

页码：297 / 299

页数：3

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