Transient free radicals are formed during photolysis of the 1-(2-nitrophenyl) ethyl ester of adenosine triphosphate (caged ATP)

被引：4

作者：

Corrie, JET

Baker, J

Ostap, EM

Thomas, DD

Trentham, DR

机构：

[1] Natl Inst Med Res, London NW7 1AA, England

[2] Univ Minnesota, Sch Med, Dept Biochem, Minneapolis, MN 55455 USA

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 1998年 / 115卷 / 01期

基金：

美国国家卫生研究院;

关键词：

transient free radicals; photolysis; adenosine triphosphate;

D O I：

10.1016/S1010-6030(98)00231-7

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Flash photolysis of the P-3-1-(2-nitrophenyl)ethyl ester of ATP (caged ATF) in thr presence of dithiothreitol results in formation of a transient radical species in addition to the known paired-electron aci-nitro anion. The transient radical represents approx, 10% of the reaction flux and is proposed to be the radical anion of the nitroaryl group of caged ATP. The kinetics of its formation suggest that it arises by single electron transfer to the triplet excited state of the nitroarene. The electron donor has not been conclusively identified but tertiary amines present as buffer salts or as impurities are likely candidates. (C) 1998 Elsevier Science S.A. All rights reserved.

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页码：49 / 55

页数：7

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