Photoresponsive polypeptides

被引：190

作者：

Pieroni, O ^{[1
]}

Fissi, A

Angelini, N

Lenci, F

机构：

[1] CNR, Inst Biophys, Area Ric, I-56010 Pisa, Italy

[2] Univ Pisa, Dept Chem & Ind Chem, I-56100 Pisa, Italy

[3] Univ Parma, Dept Phys, UdR Parma, INFM, I-43100 Parma, Italy

来源：

ACCOUNTS OF CHEMICAL RESEARCH | 2001年 / 34卷 / 01期

关键词：

D O I：

10.1021/ar990141+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Polypeptides containing azobenzene or spiropyran units attached to the macromolecules respond to light or dark conditions giving reversible variations of their structure. In this Account we provide a short overview of current research in the field and describe the most significant experimental examples of photoresponse effects. They include photoinduced random coil/alpha -helix transitions, helix-sense reversal, photostimulated aggregation/disaggregation processes, and photomechanical effects. These fascinating properties suggest that photoresponsive polypeptides may became suitable materials for designing sensors and devices that can be photomodulated. Findings also demonstrate that it is possible to synthesize model systems which respond to light similarly to naturally occurring photoreceptors.

引用

页码：9 / 17

页数：9

共 52 条

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