Cardiac function and oxygen balance in septic patients during continuous hemofiltration

被引：4

作者：

Meloni, C ^{[1
]}

Morosetti, M ^{[1
]}

Turani, F ^{[1
]}

Palombo, G ^{[1
]}

Meschini, L ^{[1
]}

Zupancich, E ^{[1
]}

Taccone-Gallucci, M ^{[1
]}

Di Giulio, S ^{[1
]}

Casciani, CU ^{[1
]}

机构：

[1] NCR, Inst Tissue Typing, Laquila, Italy

来源：

BLOOD PURIFICATION | 1998年 / 16卷 / 03期

关键词：

septic shock; multiple organ failure; acute renal failure; continuous hemofiltration;

D O I：

10.1159/000014327

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of this work was to study hemodynamic, oximetric and metabolic parameters in septic patients during continuous hemofiltration, in order to determine whether the changes in hemodynamic parameters can influence the oxygen utilization in peripheral tissues, 29 multiple organ failure patients with septic shock were studied during the first 48 h of continuous hemofiltration: 18 were submitted to CAVH and 11 patients were treated with CAVHD to correct ARF and fluid overload. Our data show that RVEF improves and REDVI reduces progressively during treatment, together with a significant reduction of the cardiac index after 48 h of CAVH(D). There were no significant variations in oxygen tissue parameters, while plasma lactate was reduced significantly, In conclusion, our data confirm that continuous hemofiltration may be useful in septic patients to correct fluid overload and ARF, without affecting hemodynamic stability and oxygen balance. Moreover, in septic patients, this technique improves hemodynamics, reduces the filling pressure in the right heart and reduces hyperdynamic response as CI and SVRI, without any negative effects on O-2 balance.

引用

页码：140 / 146

页数：7

共 29 条

[1] A PROSPECTIVE-STUDY OF CONTINUOUS HEMODIAFILTRATION IN THE MANAGEMENT OF SEVERE ACUTE-RENAL-FAILURE IN CRITICALLY ILL SURGICAL PATIENTS [J].