Emergence of Metallo-β-Lactamase NDM-1-Producing Multidrug-Resistant Escherichia coli in Australia

被引：203

作者：

Poirel, Laurent ^{[1
,2
]}

Lagrutta, Emilie ^{[1
,2
]}

Taylor, Peter ^{[3
]}

Pham, Jeanette ^{[3
]}

Nordmann, Patrice ^{[1
,2
]}

机构：

[1] Hop Bicetre, AP HP, Emerging Resistance Antibiot U914, INSERM,Fac Med,Serv Bacteriol Virol, K Bicetre, France

[2] Univ Paris Sud, K Bicetre, France

[3] Prince Wales Hosp, Dept Microbiol, S Eastern Area Lab Serv, Sydney, NSW, Australia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2010年 / 54卷 / 11期

关键词：

PSEUDOMONAS-AERUGINOSA; DIVERSITY;

D O I：

10.1128/AAC.00878-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A multidrug-resistant Escherichia coli isolate recovered in Australia produced a carbapenem-hydrolyzing beta-lactamase. Molecular investigations revealed the first identification of the bla(NDM-1) metallo-beta-lactamase gene in that country. In addition, this E. coli isolate expressed the extended-spectrum beta-lactamase CTX-M-15, together with two 16S rRNA methylases, namely, ArmA and RmtB, conferring a high level of resistance to aminoglycosides.

引用

页码：4914 / 4916

页数：3

共 19 条

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