Measurement errors and their consequences in protein crystallography

被引：64

作者：

Borek, D

Minor, W

Otwinowski, Z

机构：

[1] Univ Texas, SW Med Ctr, Dept Biochem, Dallas, TX 75390 USA

[2] Univ Virginia, Dept Mol Physiol & Biol Phys, Charlottesville, VA 22908 USA

来源：

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY | 2003年 / 59卷

关键词：

D O I：

10.1107/S0907444903020924

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This article analyzes the relative impact of various types of measurement uncertainties on different stages of structure determination. The treatment of errors is an important part of the experimental process and becomes critical when data quality is barely sufficient to solve and/or answer detailed questions about the structure. The sources and types of experimental errors are described and methods of minimizing their impact are discussed. Practical calculations of sigma estimates in DENZO and SCALEPACK are presented.

引用

页码：2031 / 2038

页数：8

共 37 条

[31] PROCESSING OSCILLATION DIFFRACTION DATA FOR VERY LARGE UNIT CELLS WITH AN AUTOMATIC CONVOLUTION TECHNIQUE AND PROFILE FITTING [J].