p16INK4:: Involvement early and often in gastrointestinal malignancies

[1] Barrett MT, 1996, ONCOGENE, V13, P1867

[2] Aberrant methylation of p16INK4a is an early event in lung cancer and a potential biomarker for early diagnosis [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (20) : 11891 - 11896

[3] FREQUENCY OF HOMOZYGOUS DELETION AT P16/CDKN2 IN PRIMARY HUMAN TUMORS [J]. NATURE GENETICS, 1995, 11 (02) : 210 - 212

[4] FREQUENT SOMATIC MUTATIONS AND HOMOZYGOUS DELETIONS OF THE P16 (MTS1) GENE IN PANCREATIC ADENOCARCINOMA [J]. NATURE GENETICS, 1994, 8 (01) : 27 - 32

[5] Germ-line mutations of the p16(INK4)(MTS1) gene occur in a subset of patients with hepatocellular carcinoma [J]. HEPATOLOGY, 1997, 25 (06) : 1376 - 1381

[6] Inactivation of p16 in human mammary epithelial cells by CpG island methylation [J]. MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (04) : 1793 - 1801

[7] GONZALEZZULUETA M, 1995, CANCER RES, V55, P4531

[8] Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE) [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (12) : 2529 - 2531

[9] HERMAN JG, 1995, CANCER RES, V55, P4525

[10] Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) : 9821 - 9826

[1] Barrett MT, 1996, ONCOGENE, V13, P1867

[2] Aberrant methylation of p16INK4a is an early event in lung cancer and a potential biomarker for early diagnosis [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (20) : 11891 - 11896

[3] FREQUENCY OF HOMOZYGOUS DELETION AT P16/CDKN2 IN PRIMARY HUMAN TUMORS [J]. NATURE GENETICS, 1995, 11 (02) : 210 - 212

[4] FREQUENT SOMATIC MUTATIONS AND HOMOZYGOUS DELETIONS OF THE P16 (MTS1) GENE IN PANCREATIC ADENOCARCINOMA [J]. NATURE GENETICS, 1994, 8 (01) : 27 - 32

[5] Germ-line mutations of the p16(INK4)(MTS1) gene occur in a subset of patients with hepatocellular carcinoma [J]. HEPATOLOGY, 1997, 25 (06) : 1376 - 1381

[6] Inactivation of p16 in human mammary epithelial cells by CpG island methylation [J]. MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (04) : 1793 - 1801

[7] GONZALEZZULUETA M, 1995, CANCER RES, V55, P4531

[8] Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE) [J]. NUCLEIC ACIDS RESEARCH, 1997, 25 (12) : 2529 - 2531

[9] HERMAN JG, 1995, CANCER RES, V55, P4525

[10] Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (18) : 9821 - 9826