Virology, pathology, and clinical manifestations of West Nile virus disease

被引:125
作者
Hayes, EB
Sejvar, JJ
Zaki, SR
Lanciotti, RS
Bode, AV
Campbell, GL
机构
[1] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Ft Collins, CO 80526 USA
[2] Ctr Dis Control & Prevent, Atlanta, GA USA
关键词
D O I
10.3201/eid1108.050289b
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
West Nile virus (WNV) causes epidemics of febrile illness, meningitis, encephalitis, and flaccid paralysis. Since it was first detected in New York City in 1999, and through 2004, > 16,000 WNV disease cases have been reported in the United States. Over the past 5 years, research on WNV disease has expanded rapidly. This review highlights new information regarding the virology, clinical manifestations, and pathology of WNV disease, which will provide a new platform for further research into diagnosis, treatment, and possible prevention of WNV through vaccination.
引用
收藏
页码:1174 / 1179
页数:6
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