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Allergic contact dermatitis elicitation thresholds of potent allergens in humans

被引：30
作者：
Jerschow, E [1 ]
Hostynek, JJ [1 ]
Maibach, HI [1 ]
机构：
[1] Univ Calif San Francisco, Sch Med, Dept Dermatol, San Francisco, CA 94143 USA
来源：
FOOD AND CHEMICAL TOXICOLOGY | 2001年 / 39卷 / 11期
关键词：
human; allergic contact dermatitis; elicitation; patch test; threshold concentration; metals; biocides;
D O I：
10.1016/S0278-6915(01)00059-X
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Literature scoured for human allergenicity to individual chemicals yields a limited number of potent sensitizers, which can be classified in four categories: metals, botanicals, biocides and miscellany. Potency is defined as strong for substances eliciting eczematous reactions to patch concentrations of 500 ppm (parts per million) or less in sensitized individuals. Most data encountered stem from studies conducted on dermatology patients tested routinely for hypersensitivity; only few data have been generated by systematic serial dilution testing. (C) 2001 Published by Elsevier Science Ltd.
引用
收藏
页码：1095 / 1108
页数：14
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