The 3' ends of almost all eukaryotic RNAs are generated by nucleolytic cleavage. Remarkably, three groups now demonstrate that similar or identical endonucleases of the metallo-beta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, and U snRNAs.
机构:
Yale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USAYale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USA
Kolev, NG
;
Steitz, JA
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机构:
Yale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USAYale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USA
机构:
Yale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USAYale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USA
Kolev, NG
;
Steitz, JA
论文数: 0引用数: 0
h-index: 0
机构:
Yale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USAYale Univ, Howard Hughes Med Inst, Dept Mol Biophys & Biochem, New Haven, CT 06536 USA