Beyond the Venn diagram: the hunt for a core microbiome

被引:841
作者
Shade, Ashley [1 ]
Handelsman, Jo [1 ]
机构
[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA
关键词
SPECIES ABUNDANCE DISTRIBUTIONS; GUT MICROBIOTA; INTESTINAL MICROBIOTA; DIVERSITY; COMMUNITIES; POPULATION; DYNAMICS; ECOLOGY; NETWORK; OBESITY;
D O I
10.1111/j.1462-2920.2011.02585.x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Discovering a core microbiome is important for understanding the stable, consistent components across complex microbial assemblages. A core is typically defined as the suite of members shared among microbial consortia from similar habitats, and is represented by the overlapping areas of circles in Venn diagrams, in which each circle contains the membership of the sample or habitats being compared. Ecological insight into core microbiomes can be enriched by 'omics approaches that assess gene expression, thereby extending the concept of the core beyond taxonomically defined membership to community function and behaviour. Parameters defined by traditional ecology theory, such as composition, phylogeny, persistence and connectivity, will also create a more complex portrait of the core microbiome and advance understanding of the role of key microorganisms and functions within and across ecosystems.
引用
收藏
页码:4 / 12
页数:9
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