Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM

被引：19

作者：

Bordigoni, P

Auburtin, B

Carret, AS

Schuhmacher, A

Humbert, JC

Le Deist, F

Sommelet, D

机构：

[1] Childrens Hosp, Bone Marrow Transplantat Unit, Nancy, France

[2] Hop Necker Enfants Malad, INSERM, U429, Paris, France

来源：

BONE MARROW TRANSPLANTATION | 1998年 / 22卷 / 11期

关键词：

X-linked immunodeficiency with hyper-IgM; bone marrow transplantation; CD40; ligand;

D O I：

10.1038/sj.bmt.1701497

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We report a 10-year-old boy with a severe form of immunodeficiency with hyper-IgM who underwent successful bone marrow transplantation with his HLA-matched sister as donor. Busulfan (20 mg/kg) and cyclophosphamide (200 mg/kg) were used as conditioning. The post-transplant course was uneventful. He is alive 25 months later with full hematological and immunological reconstitution.

引用

页码：1111 / 1114

页数：4

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