Rearranged abietane-type diterpenes from Salvia dichroantha

被引：78

作者：

Kawazoe, K

Yamamoto, M

Takaishi, Y

Honda, G

Fujita, T

Sezik, E

Yesilada, E

机构：

[1] Univ Tokushima, Fac Pharmaceut Sci, Tokushima 7708505, Japan

[2] Kyoto Univ, Fac Pharmaceut Sci, Kyoto 6068501, Japan

[3] Gazi Univ, Fac Pharm, TR-06330 Ankara, Turkey

来源：

PHYTOCHEMISTRY | 1999年 / 50卷 / 03期

关键词：

Salvia dichroantha; S-tomentosa; Labiatae; dichroanal A; dichroanal B; dichroanone; abietane;

D O I：

10.1016/S0031-9422(98)00471-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three new irregular abietane-type diterpenes were isolated from the root of Salvia dichroantha. It was revealed by spectroscopic methods and chemical reaction that these compounds have a unique structure which contains a rearranged abietane skeleton. They were named dichroanal A and B and dichroanone and shown to be rel-(4aS,9R,9aS)-8-formyl-1,2,3,4,4a,9a-hexahydro-5,6,9-trihydroxy-7-isopropyl-1,1,4a-trimethylfluorene; 4aS*-8-formyl-2,3,4,4a-tetrahydro-5,6-dihydroxy-7-isopropyl-1,1,4a-trimethyl-1H-fluorene and 4aS*-2,3,4,4a-tetrahydro-6-hydroxy-7-isopropyl-1,1,4a-trimethyl-5,8(1H)-fluorenedione, respectively. Salvia tomentosa was found to contain seven known abietane-type diterpenes. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：493 / 497

页数：5

共 8 条

[1]

ALHAZIMI HMG, 1987, PHYTOCHEMISTRY, V26, P1091, DOI 10.1016/S0031-9422(00)82356-0

[2] STRUCTURE ELUCIDATION AND TOTAL SYNTHESIS OF NEW TANSHINONES ISOLATED FROM SALVIA-MILTIORRHIZA BUNGE (DANSHEN) [J].