Pyrrolizidine alkaloids in members of the Boraginaceae from Sinai (Egypt)

被引:47
作者
El-Shazly, A
El-Domiaty, M
Witte, L
Wink, M
机构
[1] Inst Pharmazeut Biol, D-69120 Heidelberg, Germany
[2] Zagazig Univ, Fac Pharm, Dept Pharmacognosy, Zagazig, Egypt
[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Pharmazeut Biol, D-38106 Braunschweig, Germany
关键词
Paracaryum rugulosum; Paracaryum intermedium; Anchusa milleri; Gastrocotyle hispida; Anchusa arvensis; Lappula spinocarpos; Alkanna orientalis; Alkanna tubeinculata; Trichodesma africanum; Boraginaceae; pyrrolizidine alkaloids; gas liquid chromatography (GLC); GLC mass spectrometry;
D O I
10.1016/S0305-1978(98)00028-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Altogether 40 pyrrolizidine alkaloids were detected in the alkaloid extracts of Paracaryum rugulosum, P. intermedium, Anchusa milleri, Gastrocotyle hispida (syn. Anchusa hispida), Anchusa arvensis, Lappula spinocarpos, Trichodesma africanum, Alkanna orientalis, and Alkanna tuberculata (syn, A, tinctoria) which were analyzed by capillary GLC and GLC-MS. 24 alkaloids were unambiguously identified by comparing their specific retention indices and mass fragmentations with those of authentic alkaloids and literature data. The relevance of PAs as chemical defence compounds for desert plants against herbivores is discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:619 / 636
页数:18
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