Prevalence of psychiatric disorders in patients with polycystic ovary syndrome

被引:85
作者
Rassi, Arabella [1 ]
Veras, Andre Barciela [1 ]
dos Reis, Moema [1 ]
Pastore, Daniele Lauriano [1 ]
Bruno, Leandro Marchetti [1 ]
Bruno, Ricardo Vasconcellos [1 ]
Pinto de Avila, Marcio Augusto [1 ]
Nardi, Antonio E. [1 ]
机构
[1] Univ Fed Rio de Janeiro, INCT Translat Med CNPq, Inst Psychiat, Panic & Respirat Lab, BR-79020011 Rio De Janeiro, Brazil
关键词
BIPOLAR DISORDER; INSULIN-RESISTANCE; WOMEN; TESTOSTERONE; DEPRESSION; RISK;
D O I
10.1016/j.comppsych.2010.02.009
中图分类号
R749 [精神病学];
学科分类号
100204 [神经病学];
摘要
Objective: To investigate the prevalence of psychiatric disorders among women in ambulatory treatment for polycystic ovary syndrome (PCOS) and to correlate its clinical and demographic aspects with mental disorders. Methodology: Seventy-two patients in ambulatory treatment at the Endocrinal and Gynaecological Institute of the Federal University of Rio de Janeiro were evaluated using Diagnostic and Statistical Manual for Mental Disorders, Fourth Edition criteria by means of MINI (Mini International Neuropsychiatric Interview, version 4.4). Polycystic ovary syndrome was confirmed according to the ultrasonographic criteria of Adams and by clinical parameters. Results: Forty-one patients (57%) presented at least one psychiatric diagnosis. Among them, the prevalence of mood disorder reached 78%. The most prevalent diagnostics were major depression (26.4%) and bipolar disorder (11.1%). Conclusion: A high prevalence of mental disorders was observed, especially major depression and bipolar disorder. The data obtained regarding the relationship between PCOS and mood disorders in a Brazilian sample is in accordance with recent research findings in the same area. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码:599 / 602
页数:4
相关论文
共 14 条
[1]
ADAMS J, 1985, LANCET, V2, P1375
[2]
[Anonymous], 1994, DSM 4
[3]
[Anonymous], MINIINTERNATIONAL NE
[4]
Glucose intolerance in obese adolescents with polycystic ovary syndrome:: Roles of insulin resistance and β-cell dysfunction and risk of cardiovascular disease [J].
Arslanian, SA ;
Lewy, VD ;
Danadian, K .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (01) :66-71
[5]
PROFOUND PERIPHERAL INSULIN RESISTANCE, INDEPENDENT OF OBESITY, IN POLYCYSTIC OVARY SYNDROME [J].
DUNAIF, A ;
SEGAL, KR ;
FUTTERWEIT, W ;
DOBRJANSKY, A .
DIABETES, 1989, 38 (09) :1165-1174
[6]
MEDICAL PROGRESS - POLYCYSTIC-OVARY-SYNDROME [J].
FRANKS, S .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (13) :853-861
[7]
Development and validation of a screening instrument for bipolar spectrum disorder: The mood disorder questionnaire [J].
Hirschfeld, RMA ;
Williams, JBW ;
Spitzer, RL ;
Calabrese, JR ;
Flynn, L ;
Keck, PE ;
Lewis, L ;
McElroy, SL ;
Post, RM ;
Rapport, DJ ;
Russell, JM ;
Sachs, GS ;
Zajecka, J .
AMERICAN JOURNAL OF PSYCHIATRY, 2000, 157 (11) :1873-1875
[8]
Screening for bipolar disorder in women with polycystic ovary syndrome: A pilot study [J].
Klipstein, KG ;
Goldberg, JF .
JOURNAL OF AFFECTIVE DISORDERS, 2006, 91 (2-3) :205-209
[9]
Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome [J].
Nestler, JE ;
Jakubowicz, DJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (09) :617-623
[10]
RAO RC, 2001, ANN M AM PSYCH ASS M