Multifunctional magnetite and silica-magnetite nanoparticles: Synthesis, surface activation and applications in life sciences

被引：180

作者：

del Campo, A

Sen, T

Lellouche, JP

Bruce, IJ

机构：

[1] Univ Greenwich, Sch Sci, Chatham ME6 4BT, Kent, England

[2] Univ Urbino, Inst Sci Chim, I-60129 Urbino, Italy

[3] Bar Ilan Univ, Dept Chem, IL-52900 Ramat Gan, Israel

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2005年 / 293卷 / 01期

关键词：

silica-magnetite nanocomposites; surface modification; alkoxysilanes; DNA immobilisation;

D O I：

10.1016/j.jmmm.2005.01.040

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A method for the introduction of amine groups onto the surface of magnetite and silica-coated magnetite nanoparticles has been established based on the condensation of aminopropyltriethoxysilane. Amine-modified particles were grafted with an oligonucleotide and used in the capture of a complimentary sequence. The particles' efficiency at capture was observed to correlate directly with amine group surface density. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：33 / 40

页数：8

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