Funguria in cancer patients: Analysis of risk factors, clinical presentation and outcome in 50 patients

被引:15
作者
Oravcova, E
Lacka, J
Drgona, L
Studena, M
Sevcikova, L
Spanik, S
Svec, J
Kukuckova, E
Grey, E
Silva, J
Krcmery, V
机构
[1] UNIV TRNAVA, NCI, DEPT MED, TRNAVA 91743, SLOVAKIA
[2] COMENIUS UNIV BRATISLAVA, SCH MED, DEPT ONCOL, BRATISLAVA, SLOVAKIA
[3] POSTGRAD MED SCH, DEPT CHEMOTHERAPY, BRATISLAVA, SLOVAKIA
[4] UNIV CALIF DAVIS, DEPT MED, DAVIS, CA 95616 USA
[5] SLOVAK UNIV TECHNOL BRATISLAVA, DEPT COMP, BRATISLAVA, SLOVAKIA
关键词
D O I
10.1007/BF01743368
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Fifty cancer patients with funguria of > 10(5) CFU/ml, dysuria and leukocyturia were retrospectively analyzed for etiology, risk factors and outcome. In 72% of cases Candida albicans and in 28% non-albicans Candida spp, (Candida krusei, Candida tropicalis) and non-Candida spp, yeasts (Blastoschizomyces capitatus) were isolated. Torulopsis glabrata was not found among these patients, The most frequent risk factors were: antibiotic therapy with more than one antibiotic agent (96%), concomitant fungal infection in other localizations than the urinary tract (36%), colonization with the same species (48%), catheterization with urinary catheter or nephrostomy (46%), prophylaxis with quinolones (50%) and previous therapy with corticosteroids (72%). Structural or anatomic malformations of the urinary tract (26%), neutropenia (28%), antifungal prophylaxis with azoles (22%), and diabetes mellitus (12%) were less frequently seen, Thirty of 36 patients treated with systemic antifungals were cured and six were not.
引用
收藏
页码:319 / 323
页数:5
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