Plasma vanillylmandelic acid level as an index of psychological stress response in normal subjects

被引:23
作者
Fukuda, M
Hata, A
Niwa, SI
Hiramatsu, KI
Honda, H
Nakagome, K
Iwanami, A
机构
[1] FUKUSHIMA MED COLL, DEPT PSYCHIAT, FUKUSHIMA, JAPAN
[2] SHOWA UNIV, SCH MED, DEPT NEUROPSYCHIAT, TOKYO 142, JAPAN
关键词
3-methoxy-4-hydroxyphenylglycol; anxiety; cortisol; homovanillic acid; 5-hydroxyindolacetic acid;
D O I
10.1016/0165-1781(96)02527-9
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The relationships between psychological stress responses and plasma levels of vanillylmandelic acid (VMA), 3-methoxy-4-hydroxyphenylglycol (MHPG), homovanillic acid (HVA), and 5-hydroxyindolacetic acid (5-HIAA) were investigated in normal volunteers. Two questionnaires were used to measure stress: the Psychological Stress Response Scale (PSRS) and the State-Trait Anxiety Inventory (STAI). Plasma levels of VMA - but not MHPG, HVA, and 5-HIAA - showed significant positive correlations with PSRS emotional and cognitive-behavioral stress and STAI state anxiety, Significant positive correlations were also found between plasma levels of VMA and MHPG and psychological stress responses measured repeatedly in a longitudinal study of an Olympic swimmer. Plasma VMA measurements, which reflect the level of activity of the peripheral sympathetic nervous system, may provide a useful biochemical index of psychological stress responses in normal subjects.
引用
收藏
页码:7 / 16
页数:10
相关论文
共 40 条
  • [1] Abercrombie Elizabeth D., 1995, P355
  • [2] Akil Huda A., 1995, P773
  • [3] HOMOVANILLIC-ACID MEASUREMENT IN CLINICAL RESEARCH - A REVIEW OF METHODOLOGY
    AMIN, F
    DAVIDSON, M
    DAVIS, KL
    [J]. SCHIZOPHRENIA BULLETIN, 1992, 18 (01) : 123 - 148
  • [4] ASSESSMENT OF THE CENTRAL DOPAMINERGIC INDEX OF PLASMA HVA IN SCHIZOPHRENIA
    AMIN, F
    DAVIDSON, M
    KAHN, RS
    SCHMEIDLER, J
    STERN, R
    KNOTT, PJ
    APTER, S
    [J]. SCHIZOPHRENIA BULLETIN, 1995, 21 (01) : 53 - 66
  • [5] ATTERHOG JH, 1981, BRIT HEART J, V46, P311
  • [6] REPRODUCIBILITY OF THE MEASUREMENT OF PLASMA NORADRENERGIC AND DOPAMINERGIC METABOLITES IN NORMAL SUBJECTS
    BAKER, NJ
    ADLER, LE
    WALDO, M
    GERHARDT, G
    DREBING, C
    COX, B
    BERRY, S
    PHILLIPS, W
    FREEDMAN, R
    [J]. PSYCHIATRY RESEARCH, 1988, 23 (02) : 119 - 130
  • [7] CHARNEY DS, 1984, ARCH GEN PSYCHIAT, V41, P751
  • [8] Cronbach LJ, 1951, PSYCHOMETRIKA, V16, P297
  • [9] THE EFFECT OF AGE, SEX, WEIGHT AND HEIGHT ON THE PLASMA-CONCENTRATIONS IN HEALTHY-SUBJECTS OF THE ACIDIC METABOLITES OF SOME BIOGENIC MONOAMINES INVOLVED IN PSYCHIATRIC AND NEUROLOGICAL DISORDERS
    DAVIS, BA
    DURDEN, DA
    OREILLY, RL
    [J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1991, 15 (04) : 503 - 512
  • [10] SHORT-TERM CATECHOLAMINE RESPONSE TO PSYCHOLOGICAL STRESS
    DIMSDALE, JE
    MOSS, J
    [J]. PSYCHOSOMATIC MEDICINE, 1980, 42 (05): : 493 - 497