The genomic island SGI1, containing the multiple antibiotic resistance region of Salmonella enterica serovar typhimurium DT104 or variants of it, is widely distributed in other S-enterica serovars

被引:153
作者
Levings, RS
Lightfoot, D
Partridge, SR
Hall, RM
Djordjevic, SP
机构
[1] New S Wales Dept Primary Ind, Elizabeth Macarthur Agr Inst, Microbiol & Immunol Sect, Camden, NSW 2570, Australia
[2] Univ Wollongong, Dept Biol Sci, Wollongong, NSW 2522, Australia
[3] Macquarie Univ, Dept Biol Sci, Sydney, NSW 2109, Australia
[4] Univ Sydney, Sch Mol & Microbial Biosci, Sydney, NSW 2006, Australia
关键词
D O I
10.1128/JB.187.13.4401-4409.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The global dissemination of the multiply-antibiotic-resistant Salmonella enterica serovar Typhimurimn DT104 clone with the resistance genes located in a class 1 integron, here designated In104, within genomic island SGI1 is a significant public health issue. Here, we have shown that SGI1 and variants of it carrying different combinations of resistance genes are found in several Salmonella enterica serovars. These are serovars Cerro, Derby, Dusseldorf, Infantis, Kiambu, and Paratyphi B dT(+) isolated from human infections and serovar Emek from sewage effluent. Two new variants, SGI1-I and SGI1-J, both of which include the dfrA1-orfC cassette array, were identified.
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收藏
页码:4401 / 4409
页数:9
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