Resistance to an herbivore through engineered cyanogenic glucoside synthesis

被引:200
作者
Tattersall, DB
Bak, S
Jones, PR
Olsen, CE
Nielsen, JK
Hansen, ML
Hoj, PB
Moller, BL
机构
[1] Royal Vet & Agr Univ, Dept Plant Biol, Plant Biochem Lab, DK-1871 Frederiksberg C, Denmark
[2] Royal Vet & Agr Univ, Ctr Mol Plant Physiol, DK-1871 Frederiksberg C, Denmark
[3] Royal Vet & Agr Univ, Dept Chem, DK-1871 Frederiksberg C, Denmark
[4] Univ Adelaide, Dept Hort Viticulture & Oenol, Glen Osmond, SA 5064, Australia
[5] Australian Wine Res Inst, Glen Osmond, SA 5064, Australia
关键词
D O I
10.1126/science.1062249
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The entire pathway for synthesis of the tyrosine-derived cyanogenic glucoside dhurrin has been transferred from Sorghum bicolor to Arabidopsis thaliana. Here, we document that genetically engineered plants are able to synthesize and store large amounts of new natural products. The presence of dhurrin in the transgenic A. thaliana plants confers resistance to the flea beetle Phyllotreta nemorum, which is a natural pest of other members of the crucifer group, demonstrating the potential utility of cyanogenic glucosides in plant defense.
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页码:1826 / 1828
页数:3
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