Biopsy of the mouse prostate

被引:14
作者
Harmelin, A [1 ]
Danon, T
Kela, I
Brenner, O
机构
[1] Weizmann Inst Sci, Dept Vet Resources, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Dept Immunol, IL-76100 Rehovot, Israel
关键词
prostate gland; prostate cancer; prostate biopsy; mouse; animal models;
D O I
10.1258/0023677053739756
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Many transgenic and knockout mouse models of prostate cancer have become available over the past decade. In this paper we describe a simple biopsy technique of the murine prostate. This technique allows sequential follow-up of the prostate in an individual mouse. Its use could also reduce the number of mice used in studies of the prostate gland.
引用
收藏
页码:215 / 220
页数:6
相关论文
共 11 条
[1]  
Abate-Shen Cory, 2002, Trends Genet, V18, pS1, DOI 10.1016/S0168-9525(02)02683-5
[2]   PROSTATE-CANCER IN A TRANSGENIC MOUSE [J].
GREENBERG, NM ;
DEMAYO, F ;
FINEGOLD, MJ ;
MEDINA, D ;
TILLEY, WD ;
ASPINALL, JO ;
CUNHA, GR ;
DONJACOUR, AA ;
MATUSIK, RJ ;
ROSEN, JM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (08) :3439-3443
[3]  
Huang JP, 2002, CANCER RES, V62, P4812
[4]   Autochthonous mouse models for prostate cancer: past, present and future [J].
Huss, WJ ;
Maddison, LA ;
Greenberg, NM .
SEMINARS IN CANCER BIOLOGY, 2001, 11 (03) :245-259
[5]   Pathobiology of autochthonous prostate cancer in a pre-clinical transgenic mouse model [J].
Kaplan-Lefko, PJ ;
Chen, TM ;
Ittmann, MM ;
Barrios, RJ ;
Ayala, GE ;
Huss, WJ ;
Maddison, LA ;
Foster, BA ;
Greenberg, NM .
PROSTATE, 2003, 55 (03) :219-237
[6]   Genetically modified mice and their use in developing therapeutic strategies for prostate cancer [J].
Kasper, S ;
Smith, JA .
JOURNAL OF UROLOGY, 2004, 172 (01) :12-19
[7]  
Masumori N, 2001, CANCER RES, V61, P2239
[8]   Mechanisms of disease: Prostate cancer [J].
Nelson, WG ;
De Marzo, AM ;
Isaacs, WB .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (04) :366-381
[9]  
SHAPPELL S, 2004, ANATOMIC CONSIDERATI
[10]   Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer [J].
Wang, SY ;
Gao, J ;
Lei, QY ;
Rozengurt, N ;
Pritchard, C ;
Jiao, J ;
Thomas, GV ;
Li, G ;
Roy-Burman, P ;
Nelson, PS ;
Liu, X ;
Wu, H .
CANCER CELL, 2003, 4 (03) :209-221