EuroPhenome and EMPReSS: online mouse phenotyping resource

被引:55
作者
Mallon, Ann-Marie [1 ]
Blake, Andrew [1 ]
Hancock, John M. [1 ]
机构
[1] MRC, Mammalian Genet Unit, Didcot OX11 0RD, Oxon, England
基金
英国医学研究理事会;
关键词
D O I
10.1093/nar/gkm728
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
EuroPhenome (http://www.europhenome.org) and EMPReSS (http://empress.har.mrc.ac.uk/) form an integrated resource to provide access to data and procedures for mouse phenotyping. EMPReSS describes 96 Standard Operating Procedures for mouse phenotyping. EuroPhenome contains data resulting from carrying out EMPReSS protocols on four inbred laboratory mouse strains. As well as web interfaces, both resources support web services to enable integration with other mouse phenotyping and functional genetics resources, and are committed to initiatives to improve integration of mouse phenotype databases. EuroPhenome will be the repository for a recently initiated effort to carry out large-scale phenotyping on a large number of knockout mouse lines (EUMODIC).
引用
收藏
页码:D715 / D718
页数:4
相关论文
共 13 条
[1]   Mouse Phenome Database (MPD) [J].
Bogue, Molly A. ;
Grubb, Stephen C. ;
Maddatu, Terry P. ;
Bult, Carol J. .
NUCLEIC ACIDS RESEARCH, 2007, 35 :D643-D649
[2]   EMPReSS: standardized phenotype screens for functional annotation of the mouse genome [J].
Brown, SDM ;
Chambon, P ;
de Angelis, MH .
NATURE GENETICS, 2005, 37 (11) :1155-1155
[3]   Understanding mammalian genetic systems: The challenge of phenotyping in the mouse [J].
Brown, Steve D. M. ;
Hancock, John M. ;
Gates, Hilary .
PLOS GENETICS, 2006, 2 (08) :1131-1137
[4]   A mouse for all reasons [J].
Collins, Francis S. .
CELL, 2007, 128 (01) :9-13
[5]   N-ethyl-N-nitrosourea mutagenesis:: Boarding the mouse mutant express [J].
Cordes, SP .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 2005, 69 (03) :426-+
[6]   The Ontology Lookup Service, a lightweight cross-platform tool for controlled vocabulary queries [J].
Côté, RG ;
Jones, P ;
Apweiler, R ;
Hermjakob, H .
BMC BIOINFORMATICS, 2006, 7 (1)
[7]  
Gkoutos G V, 2004, Pac Symp Biocomput, P178
[8]   Using ontologies to describe mouse phenotypes [J].
Georgios V Gkoutos ;
Eain CJ Green ;
Ann-Marie Mallon ;
John M Hancock ;
Duncan Davidson .
Genome Biology, 6 (1)
[9]   EMPReSS: European Mouse Phenotyping Resource for Standardized Screens [J].
Green, ECJ ;
Gkoutos, GV ;
Lad, HV ;
Blake, A ;
Weekes, J ;
Hancock, JM .
BIOINFORMATICS, 2005, 21 (12) :2930-2931
[10]   Integration of mouse phenome data resources [J].
Hancock, John M. ;
Adams, Niels C. ;
Aidinis, Vassilis ;
Blake, Andrew ;
Blake, Judith A. ;
Bogue, Molly ;
Brown, Steve D. M. ;
Chesler, Elissa ;
Davidson, Duncan ;
Duran, Christopher ;
Eppig, Janan T. ;
Gailus-Durner, Valerie ;
Gates, Hilary ;
Gkoutos, Georgios V. ;
Greenaway, Simon ;
De Angelis, Martin Hrabe ;
Kollias, George ;
Leblanc, Sophie ;
Lee, Kirsty ;
Lengger, Christoph ;
Maier, Holger ;
Mallon, Ann-Marie ;
Masuya, Hiroshi ;
Melvin, David G. ;
Mueller, Werner ;
Parkinson, Helen ;
Proctor, Glenn ;
Reuveni, Eli ;
Schofield, Paul ;
Shukla, Aadya ;
Smith, Cynthia ;
Toyoda, Tetsuro ;
Vasseur, Laurent ;
Wakana, Shigeharu ;
Walling, Alison ;
White, Jacqui ;
Wood, Joe ;
Zouberakis, Michalis .
MAMMALIAN GENOME, 2007, 18 (03) :157-163