Myelin: Delivery by raft

被引:35
作者
Lee, AG [1 ]
机构
[1] Univ Southampton, Div Biochem & Mol Biol, Sch Biol Sci, Southampton SO16 7PX, Hants, England
关键词
D O I
10.1016/S0960-9822(01)00008-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent results suggest that membrane proteins are delivered to the myelin sheath of an oligodendrocyte on rafts with a distinctive lipid composition. The major intrinsic membrane protein of myelin, proteolipid protein, interacts with rafts in oligodendrocytes but not with the different rafts found in other cell types.
引用
收藏
页码:R60 / R62
页数:3
相关论文
共 16 条
[1]   Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis [J].
Bosio, A ;
Binczek, E ;
Stoffel, W .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (23) :13280-13285
[2]   New perspectives on the function of myelin galactolipids [J].
Coetzee, T ;
Suzuki, K ;
Popko, B .
TRENDS IN NEUROSCIENCES, 1998, 21 (03) :126-130
[3]   Myelination in the absence of galactocerebroside and sulfatide: Normal structure with abnormal function and regional instability [J].
Coetzee, T ;
Fujita, N ;
Dupree, J ;
Shi, R ;
Blight, A ;
Suzuki, K ;
Suzuki, K ;
Popko, B .
CELL, 1996, 86 (02) :209-219
[4]  
IPSEN JH, 1987, BIOCHIM BIOPHYS ACTA, V905, P162
[5]   PHASES AND PHASE-TRANSITIONS OF THE SPHINGOLIPIDS [J].
KOYNOVA, R ;
CAFFREY, M .
BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM, 1995, 1255 (03) :213-236
[6]   VIP21, A 21-KD MEMBRANE-PROTEIN IS AN INTEGRAL COMPONENT OF TRANS-GOLGI-NETWORK-DERIVED TRANSPORT VESICLES [J].
KURZCHALIA, TV ;
DUPREE, P ;
PARTON, RG ;
KELLNER, R ;
VIRTA, H ;
LEHNERT, M ;
SIMONS, K .
JOURNAL OF CELL BIOLOGY, 1992, 118 (05) :1003-1014
[7]   LIPID PHASE-TRANSITIONS AND PHASE-DIAGRAMS .1. LIPID PHASE-TRANSITIONS [J].
LEE, AG .
BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 472 (02) :237-281
[8]   Glycosphingolipids are not essential for formation of detergent-resistant membrane rafts in melanoma cells -: Methyl-β-cyclodextrin does not affect cell surface transport of a GPI-anchored protein [J].
Ostermeyer, AG ;
Beckrich, BT ;
Ivarson, KA ;
Grove, KE ;
Brown, DA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (48) :34459-34466
[9]  
SCHMITT FO, 1985, ANNU REV BIOPHYS BIO, V14, P1
[10]   Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy [J].
Schütz, GJ ;
Kada, G ;
Pastushenko, VP ;
Schindler, H .
EMBO JOURNAL, 2000, 19 (05) :892-901