HERV-W-related RNA detected in plasma from individuals with recent-onset schizophrenia or schizoaffective disorder

被引：70

作者：

Karlsson, H ^{[1
]}

Schröder, J

Bachmann, S

Bottmer, C

Yolken, RH

机构：

[1] Karolinska Inst, Dept Neurosci, Stockholm, Sweden

[2] Univ Heidelberg, Sect Geriatr Psychiat, Heidelberg, Germany

[3] Johns Hopkins Univ, Sch Med, Stanley Div Dev Neurovirol, Baltimore, MD USA

来源：

MOLECULAR PSYCHIATRY | 2004年 / 9卷 / 01期

关键词：

D O I：

10.1038/sj.mp.4001439

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The authors previously reported that certain patients, suffering from recent-onset schizophrenia or schizoaffective disorder, harbor differentially detectable levels of endogenous retroviral RNA in CSF when compared to healthy control individuals. Presently, the authors report that, in plasma, retroviral RNA is more prevalent among patients than healthy control individuals. Further studies aiming at identifying the role of retroviral transcripts in the etiopathogenesis of schizophrenia are warranted.

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页码：12 / 13

页数：3

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